琼森（凯拉·塞吉维克 Kyra Sedgwick 饰）由亚特兰大远赴洛杉矶，担任特别罪案调查组的代理警长一职，专门调查那些令警方赶到棘手、让媒体赶到兴奋的凶杀案。这听起来风光无限的职位真正干起来却麻烦多多，因为琼森要面对的手下，是一帮固执的大男人，他们各有各的性格和想法，并且都自认为自己才是最聪明的那一个。 　　然而，随着时间的推移，琼森渐渐获得了警探们的认可和信任，每一次，她都能够凭借着自己独特的智慧和手段，从那些穷凶极恶的犯罪分子口中套出她想要得到的确凿证据，甚至有一些看似无解的案件，只有琼森一人能够破解。在琼森的带领下，整个调查组的气势愈发高涨。Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.