在一个演员家庭中，大姐汉娜（米亚·法罗 Mia Farrow 饰）的丈夫——经济人埃利奥特（迈克尔·凯恩 Michael Caine 饰）正为小姨子莉（芭芭拉·赫希 Barbara Hershey 饰）神魂颠倒。二姐霍莉（黛安娜·维斯特 Dianne Wiest 饰）戒 掉了毒品，如今为经济拮据苦恼正考虑赚钱的生意，而汉娜的前夫——电视台编导米基（伍迪·艾伦 Woody Allen 饰）终日幻觉自己得了脑肿瘤，四处求医痛苦不堪。小妹莉与孤僻的画家情人弗雷德里克（马克斯·冯·西多 Max von Sydow 饰）相处，是后者唯一的倾诉对象。埃利奥特难耐情欲，终于与莉发生了关系，霍莉在一连串打击后意外的获得了事业和爱情的拯救……围绕在这个演员家庭周围的所有人，经历着情感和事业的重新洗牌。Hannah, Holly and Lee are adult sisters from a show business family, their boozy actress mother who still believes she's an ingénue that can attract any man she wants, despite still being married to the girls' father, Evan. Hannah, on her second marriage to a man named Elliot, a financial advisor, is the success of the family, taking a break from her acting career to raise her children. Everyone turns to her for advice, while she never talks to others about what she needs or feels. Her first husband, Mickey, is a comedy show writer and hypochondriac, who is going through a crisis as he mistakenly believes he will die soon without a clear belief, as a non-practicing Jew, of what will happen to him in the afterlife. Single Holly is the insecure flaky sister, a struggling and thus continually unemployed actress, who has just started a catering business with her actress friend April, in order to do something constructive with her life. In her own security, Hannah even set up Holly and Mickey together following her own break-up with Mickey, Holly and Mickey's sole date which arguably was the worst night in both their lives. Holly turns to Hannah for everything in her life, including money, despite feeling Hannah overly judgmental about her failures. It's during a catering job that Holly and April meet David, an architect, who seems interested in both of them. Holly's insecurities may threaten her potential relationship with David and friendship with April. Lee, who collects unemployment, is metaphorically the family's piece of clay waiting for the right artist to mold her. She has long lived with artist Frederick, who has contempt for everyone except her, and as such relies on her for whatever his connection to the outside world. This already complex collective becomes even more complex when Elliot contemplates telling Lee that he has fallen in love with her. His attraction to her is as much feeling unneeded by Hannah, who he does not want to hurt regardless of what he decides to do with respect to Lee.