背景安排在位于南美小镇上的一间小诊所，故事围绕理想主义者Lily Brenner医生（Caroline Dhavernas饰）和她的友情团队之间展开，他们都是为了逃避心魔的纠缠而远走异国他乡。小诊所的创办人Ben Keeton（Martin Henderson饰）和他的得力助手（Jason George饰）帮助年轻医生学会如何在具有挑战性的环境下挽救生命。This series follows doctors working in a clinic in a South American jungle. The head of the clinic is Ben Keeton. Otis Cole is doctor who had a substance abuse problem. Zita Alvarez is Ben's right hand. Lily Brenner is trying to cope with a loss. Tommy Fuller who is an easy going guy, who makes mistakes. Mina Minard, a doctor who made a mistake which affected her confidence. And Ryan Clark, a doctor whom Ben likes.