托马斯（迪伦·欧布莱恩 Dylan O'Brien 饰）、米诺（李基弘 Ki Hong Lee 饰）一行人被带到一座神秘的庇护所，这个机构由表里不一的詹森（艾丹·吉伦 Aidan Gillen 饰）所管理，詹森为他们提供安稳且舒适的环境，并下令让幽地斗士们在医疗实验室中接受一连串的测试，詹森向托马斯保证将会把他们送到更加安全的保护区与其他对“闪焰症病毒”免疫的年轻人一同居住。察觉事有蹊跷的托马斯决定再次带领他的伙伴们逃出詹森的掌控，然而等待他们的，却是比迷宫更加危险的焦土。 　　影片改编自詹姆斯·达什纳撰写的同名反乌托邦科幻小说三部曲的第二部。The second chapter of the epic "Maze Runner" saga. Thomas (Dylan O'Brien) and his fellow Gladers face their greatest challenge yet: searching for clues about the mysterious and powerful organization known as WCKD. Their journey takes them to the Scorch, a desolate landscape filled with unimaginable obstacles. Teaming up with resistance fighters, the Gladers take on WCKD's vastly superior forces and uncover its shocking plans for them all.