英国政府派007邦德（肖恩·康纳利 Sean Connery 饰）前往加勒比海调查一桩情报人员被杀案件，007几经调查，推测死者应该与蟹礁岛上的诺博士有关。诺博士在这个神秘的小岛上正进行着不为人知的阴谋计划，紧锣密鼓进行一项将要统治世界的科学实验。双方开始了斗智斗勇的战 争，诺博士派来了女间谍，企图监测007的一举一动乘机将其制服，不料反被007识破诡计。而渔民库洛及潜水员莱特（乌苏拉·安德丝 Ursula Andress 饰）成为了007的得力助手，然而，诺博士对007此行早有准备，007与美女助手陷入重重困境。眼看007就要葬身荒岛，事情却来了惊天逆转。James Bond (007) is Britain's top agent and is on an exciting mission, to solve the mysterious murder of a fellow agent. The task sends him to Jamaica, where he joins forces with Quarrel and a loyal CIA agent, Felix Leiter. While dodging tarantulas, "fire breathing dragons" and a trio of assassins, known as the three blind mice. Bond meets up with the beautiful Honey Ryder and goes face to face with the evil Dr. No.