一批名人被一名神秘的变态杀手谋杀了，刑警Harry Callahan要查出这名杀手并制止他下一步的犯罪，他自己的名字也被列在杀手的黑名单上。在追查这名变态凶手的过程中，遇到了难缠的女记者Samantha牵涉其中，作风强悍的Harry Callahan深感头痛。Harry Callahan - or Dirty Harry as he is known from the previous four movies in this series - is investigating a strange betting game. A list of local celebrities has been handed out, and bets are being taken on who will be the first to die. Things start to get interesting when the name 'Harry Callahan' appears on the list.