影片用一封无法投递的信件串联起梵高在去世前最后六周里与他生命中最重要的三个人物之间的秘密，带观众穿越回十九世纪末的欧洲，并陪伴梵高走完他最后的人生。影片采用梵高原画作品中的人物原型还原梵高的艺术人生，让观众在享受美得令人窒息的视觉盛宴时，抽丝剥茧地发现隐藏了一个半世纪的秘密。A year after the death of the artist, Vincent van Gough, Postman Roulin gets his slacker son, Armand, to hand deliver the artist's final letter to his now late brother, Theo, to some worthy recipient after multiple failed postal delivery attempts. Although disdainful of this seemingly pointless chore, Armand travels to Auvers-sur-Oise where a purported close companion to Vincent, Dr. Gachet, lives. Having to wait until the doctor returns from business, Armand meets many of the people of that village who not only knew Vincent, but were apparently also models and inspirations for his art. In doing so, Armond becomes increasingly fascinated in the psyche and fate of van Gough as numerous suspicious details fail to add up. However, as Armond digs further, he comes to realize that Vincent's troubled life is as much a matter of interpretation as his paintings and there are no easy answers for a man whose work and tragedy would only be truly appreciated in the future.