洛哈特（戴恩·德哈恩 Dane DeHaan 饰）被派往位于阿尔卑斯山的一间疗养院中，接回在此疗养的公司CEO。在回程的路上，洛哈特遭遇了车祸，左腿骨折，无奈之下，他只得在疗养院中暂时停留养病。在疗养院中，洛哈特结识了神秘的少女汉娜（米娅·高斯 Mia Goth 饰）。 　　疗养院中诡异的气氛和洛哈特周围发生的接二连三的科学无法解释的事件让洛哈特开始对疗养院的经营性质产生了怀疑。汉娜和主治医生福尔摩（詹森·艾萨克 Jason Isaacs 饰）之间的暧昧关系更让洛哈特察觉到事件的不单纯。终于，洛哈特识破了隐藏在这间疗养院之中的秘密，与此同时，他的噩梦也开始了。An ambitious young executive is sent to retrieve his company's CEO from an idyllic but mysterious "wellness center" at a remote location in the Swiss Alps. He soon suspects that the spa's miraculous treatments are not what they seem. When he begins to unravel its terrifying secrets, his sanity is tested, as he finds himself diagnosed with the same curious illness that keeps all the guests here longing for the cure.